Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | STAMBP | O95630 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975150 | 1.00 | EIF4E (0.44) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL24975148 | 0.91 | ALDH1A1 (0.44) | HTTLMNAALDH1A1MAPTHPGDS | |
| SCHEMBL29801199 | 0.91 | ALDH1A1 (0.44) | HTTLMNAALDH1A1MAPTHPGDS | |
| SCHEMBL29800935 | 0.90 | NAMPT (0.51) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL24975149 | 0.90 | NAMPT (0.51) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL24975321 | 0.88 | NAMPT (0.49) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL29801142 | 0.88 | NAMPT (0.49) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL24975327 | 0.87 | EIF4E (0.45) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL29801044 | 0.87 | EIF4E (0.45) | EIF4EHTTLMNAALDH1A1MAPT | |
| SCHEMBL24975282 | 0.87 | HPGDS (0.49) | HTTLMNAALDH1A1MAPTHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |