Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975148 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL24975150 | 0.91 | EIF4E (0.44) | ALDH1A1LMNAHTTMAPTHPGDS | |
| SCHEMBL29801005 | 0.91 | EIF4E (0.44) | ALDH1A1LMNAHTTMAPTHPGDS | |
| SCHEMBL29801056 | 0.89 | LMNA (0.43) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL24975329 | 0.89 | LMNA (0.43) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL24975356 | 0.88 | LMNA (0.48) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL29801250 | 0.88 | LMNA (0.48) | ALDH1A1LMNAHTTMAPTRECQL | |
| SCHEMBL24975282 | 0.88 | HPGDS (0.49) | ALDH1A1LMNAHTTMAPTHPGDS | |
| SCHEMBL29801098 | 0.88 | HPGDS (0.49) | ALDH1A1LMNAHTTMAPTHPGDS | |
| SCHEMBL24975468 | 0.87 | LMNA (0.43) | ALDH1A1LMNAHTTMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |