Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.58 |
| ▸ | PRKDC | P78527 | 3/20 | 0.47 |
| ▸ | ATR | Q13535 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110602 | 0.79 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL24334901 | 0.78 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL23110886 | 0.77 | PTGS2 (0.61) | PTGS2ATM | |
| SCHEMBL23110876 | 0.76 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL23093156 | 0.74 | EGFR (0.49) | — | |
| SCHEMBL22828106 | 0.74 | PTGS2 (0.75) | PTGS2ATM | |
| SCHEMBL24334941 | 0.74 | PTGS2 (0.75) | PTGS2ATM | |
| SCHEMBL23110777 | 0.73 | PTGS2 (0.64) | PTGS2 | |
| SCHEMBL558006 | 0.73 | ATR (0.57) | PRKDCATRATM | |
| SCHEMBL30098967 | 0.72 | L3MBTL1 (0.60) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4027993-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | The Broad Institute Inc. (US) | 2022-07-20 | — | — | EP | disclosed |