Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 10/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665763 | 0.86 | PRKCQ (0.46) | PRKCQPTK2BMEN1CYP1A2CYP3A4 | |
| SCHEMBL29802575 | 0.84 | STK17A (0.49) | LATS1MAPTL3MBTL1STK17A | |
| SCHEMBL19665633 | 0.84 | STK17A (0.53) | PRKCQPTK2BMEN1CYP1A2CYP3A4 | |
| SCHEMBL29290148 | 0.83 | LATS1 (0.44) | LATS1STK17AMAPK8MAPK9MAPKAPK2 | |
| SCHEMBL19665748 | 0.83 | PRKCQ (0.43) | PRKCQPTK2BMEN1CYP1A2CYP3A4 | |
| SCHEMBL29802501 | 0.82 | PRKCQ (0.38) | PRKCQPTK2BMEN1CYP1A2CYP3A4 | |
| SCHEMBL19665691 | 0.76 | PRKCQ (0.52) | PRKCQCYP3A4CYP2C9 | |
| SCHEMBL19665714 | 0.75 | SIRT5 (0.53) | PRKCQPTK2BMEN1CYP1A2CYP3A4 | |
| SCHEMBL28657267 | 0.74 | L3MBTL1 (0.47) | PRKCQPTK2BMEN1CYP1A2CYP3A4 | |
| SCHEMBL19665577 | 0.74 | PRKCQ (0.49) | PRKCQCYP3A4CYP2C9JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464287-B1 | ANIMAL AND HUMAN ANTI-MALARIAL AGENTS | CELGENE CORP (US) | 2022-06-08 | — | — | EP | disclosed |
| US-11344554-B2 | Animal and human anti-malarial agents | CELGENE CORPORATION (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344554-B2 | Animal and human anti-malarial agents | HPRT1, UMPS, PNP | LATS1 2251/4885PRKCQ 2957/4885PTK2B 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.