Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946177 | 1.00 | TDP1 (0.53) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL14830879 | 0.91 | TDP1 (0.48) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5406043 | 0.89 | TDP1 (0.56) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378143 | 0.86 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31331945 | 0.85 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378083 | 0.85 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL17107771 | 0.83 | TDP1 (0.43) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7577396 | 0.83 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2037323 | 0.82 | TDP1 (0.51) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL319055 | 0.81 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12133720-B2 | Methods and compositions for restoring homeostatic capacity of a subject | Palo Alto Investors LP (US) | 2024-11-05 | — | — | US | disclosed |
| WO-2022190064-A1 | METHODS FOR IDENTIFYING SUBJECTS WITH BETACORONAVIRUS INFECTIONS WHO ARE AT RISK OF ACUTE RESPIRATORY SYNDROME AND METHODS FOR THE TREATMENT OF SAME | VEXO PHARMACEUTICALS DMCC (AE) | 2022-09-15 | — | — | WO | disclosed |