Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31378057 | 0.94 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31248180 | 0.94 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378143 | 0.92 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5406043 | 0.92 | TDP1 (0.56) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378060 | 0.86 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2458624 | 0.85 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10140261 | 0.85 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5817718 | 0.84 | HLCS (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL739034 | 0.84 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5804916 | 0.84 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020042084-A1 | Detection of NAALADase inhibitors | BOEHRINGER INGELHEIM PHARMA KG | 2002-04-11 | — | — | US | claimed |