SCHEMBL29946177

SCHEMBL29946177

CC(C)[C@H](NC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)N[C@@H](C)C(=O)NC(CC(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ ABL1 P00519 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ PKM P14618 1/20 0.53
▸ IDE P14735 1/20 0.53
▸ MAPK1 P28482 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ RIN1 Q13671 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ FOLH1 Q04609 3/20 0.49
▸ CAPN1 P07384 2/20 0.49
▸ CA12 O43570 2/20 0.44
▸ CA1 P00915 2/20 0.44
▸ CA2 P00918 2/20 0.44
▸ CA9 Q16790 2/20 0.44
▸ CASP3 P42574 2/20 0.44
▸ CASP1 P29466 2/20 0.44
▸ CASP2 P42575 1/20 0.44
▸ CASP7 P55210 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29802482 1.00 TDP1 (0.53) TDP1MEN1ABL1LMNAPKM
SCHEMBL14830879 0.91 TDP1 (0.48) TDP1MEN1ABL1LMNAPKM
SCHEMBL5406043 0.89 TDP1 (0.56) TDP1MEN1ABL1LMNAPKM
SCHEMBL31378143 0.86 TDP1 (0.68) TDP1MEN1ABL1LMNAPKM
SCHEMBL31331945 0.85 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
SCHEMBL31378083 0.85 TDP1 (0.63) TDP1MEN1ABL1LMNAPKM
SCHEMBL17107771 0.83 TDP1 (0.43) TDP1MEN1ABL1LMNAPKM
SCHEMBL7577396 0.83 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL2037323 0.82 TDP1 (0.51) TDP1MEN1ABL1LMNAPKM
SCHEMBL319055 0.81 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-05-08 — — US disclosed
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2025-04-17 — — US disclosed
US-12139744-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2024-11-12 — — US disclosed
US-12110533-B2 Stabilisation and isolation of extracellular nucleic acids QIAGEN GMBH (DE) 2024-10-08 — — US disclosed
US-20240287574-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS QIAGEN GMBH (DE) 2024-08-29 — — US disclosed
EP-4397770-A1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PreAnalytiX GmbH (CH) 2024-07-10 — — EP disclosed
EP-3401406-B1 STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS PREANALYTIX GMBH (CH) 2023-11-29 — — EP disclosed
US-11525155-B2 Stabilisation of biological samples QIAGEN GMBH (DE) 2022-12-13 — — US disclosed
US-20220364149-A1 STABILISATION OF BIOLOGICAL SAMPLES QIAGEN GMBH (DE) 2022-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122555-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TDP1 342/4885MEN1 1662/4885ABL1 1752/4885
US-12139744-B2 Stabilisation of biological samples RNASE1, RNASEH1, EWSR1 TDP1 342/4885MEN1 1662/4885ABL1 1752/4885
US-20250146050-A1 STABILISATION OF BIOLOGICAL SAMPLES RNASE1, RNASEH1, EWSR1 TDP1 342/4885MEN1 1662/4885ABL1 1752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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