Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670619 | 0.91 | TRPV1 (0.34) | TRPV1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL29803544 | 0.91 | NAMPT (0.36) | TRPV1NAMPTMAPTMCHR1JAK1 | |
| SCHEMBL29803749 | 0.90 | IMPDH2 (0.37) | TRPV1NAMPTLMNAALDH1A1JAK1 | |
| SCHEMBL29803748 | 0.88 | NAMPT (0.40) | TRPV1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL29803457 | 0.88 | NAMPT (0.47) | NAMPTLMNASMN1; SMN2 | |
| SCHEMBL24671091 | 0.85 | NAMPT (0.47) | TRPV1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL29803594 | 0.85 | NAMPT (0.47) | TRPV1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL24670644 | 0.85 | CHRM1 (0.38) | TRPV1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL24670811 | 0.84 | TRPV1 (0.39) | TRPV1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL29803651 | 0.84 | TRPV1 (0.39) | TRPV1NAMPTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |