Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MST1R | Q04912 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669273 | 0.91 | TRPV1 (0.31) | NAMPTTRPV1WDR5 | |
| SCHEMBL29803333 | 0.91 | TRPV1 (0.37) | NAMPTTRPV1JAK1PDK4MAPT | |
| SCHEMBL29803749 | 0.90 | IMPDH2 (0.37) | NAMPTTRPV1CDK9JAK1PDK4 | |
| SCHEMBL29803726 | 0.89 | WDR5 (0.38) | NAMPTWDR5CDK9JAK1PDK4 | |
| SCHEMBL29803193 | 0.88 | NAMPT (0.40) | NAMPTTRPV1WDR5CDK9JAK1 | |
| SCHEMBL29803457 | 0.88 | NAMPT (0.47) | NAMPTESRRG | |
| SCHEMBL29803558 | 0.88 | NAMPT (0.38) | NAMPTTRPV1WDR5CDK9JAK1 | |
| SCHEMBL24669910 | 0.88 | NAMPT (0.38) | NAMPTTRPV1WDR5CDK9JAK1 | |
| SCHEMBL24670605 | 0.86 | TRPV1 (0.38) | NAMPTTRPV1WDR5 | |
| SCHEMBL29803445 | 0.86 | TRPV1 (0.38) | NAMPTTRPV1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |