Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PRKX | P51817 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571017 | 1.00 | ROCK2 (0.64) | ROCK2SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29804057 | 0.84 | ROCK2 (0.62) | ROCK2SMN1; SMN2PLAUMEN1KMT2A | |
| SCHEMBL29804411 | 0.84 | ROCK2 (0.56) | ROCK2SMN1; SMN2GSK3BCLK4NAMPT | |
| SCHEMBL28584102 | 0.84 | ROCK2 (0.56) | ROCK2SMN1; SMN2GSK3BCLK4NAMPT | |
| SCHEMBL29804195 | 0.78 | LMNA (0.66) | ROCK2SMN1; SMN2ROCK1NAMPTMEN1 | |
| SCHEMBL28577264 | 0.78 | LMNA (0.66) | ROCK2SMN1; SMN2ROCK1NAMPTMEN1 | |
| SCHEMBL29804062 | 0.78 | ROCK2 (0.63) | ROCK2CYP3A4CYP2D6CYP2C9ROCK1 | |
| SCHEMBL28574045 | 0.78 | ROCK2 (0.63) | ROCK2CYP3A4CYP2D6CYP2C9ROCK1 | |
| SCHEMBL3127521 | 0.78 | ROCK2 (1.00) | ROCK2SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8176742 | 0.78 | SMN1; SMN2 (0.81) | ROCK2SMN1; SMN2NAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961081-B | Bibenzamide urea compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-13 | — | — | CN | claimed |
| CN-112961081-B | Bibenzamide urea compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-13 | — | — | CN | disclosed |