Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804195 | 1.00 | LMNA (0.66) | LMNASMN1; SMN2HPGDROCK2KMT2A | |
| SCHEMBL28411219 | 0.88 | CNR1 (0.69) | LMNASMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL8176742 | 0.84 | SMN1; SMN2 (0.81) | LMNASMN1; SMN2ROCK2KMT2AMEN1 | |
| SCHEMBL8177075 | 0.83 | EGFR (0.65) | SMN1; SMN2HPGDKMT2AMEN1MAPT | |
| SCHEMBL3815151 | 0.82 | ALDH1A1 (0.72) | LMNASMN1; SMN2HPGDROCK2KMT2A | |
| SCHEMBL28577442 | 0.81 | EPHX2 (0.62) | LMNASMN1; SMN2ROCK2KMT2AMAPT | |
| SCHEMBL29804233 | 0.81 | EPHX2 (0.62) | LMNASMN1; SMN2ROCK2KMT2AMAPT | |
| SCHEMBL27977535 | 0.80 | HPGD (0.69) | LMNASMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL11615122 | 0.79 | NAMPT (0.83) | LMNASMN1; SMN2ROCK2ALDH1A1GAA | |
| SCHEMBL28571017 | 0.78 | ROCK2 (0.64) | LMNASMN1; SMN2ROCK2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961081-B | Bibenzamide urea compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-13 | — | — | CN | disclosed |
| CN-112961081-A | Bibenzamide urea compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2021-06-15 | — | — | CN | disclosed |