SCHEMBL29804127

SCHEMBL29804127

CC(C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)C(C)C

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 5/20 0.73
▸ OPRM1 P35372 2/20 0.58
▸ REN P00797 2/20 0.56
▸ SLC6A2 P23975 1/20 0.55
▸ ANPEP P15144 2/20 0.55
▸ LNPEP Q9UIQ6 2/20 0.55
▸ KISS1R Q969F8 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31071616 1.00 DPP3 (0.73) DPP3OPRM1RENSLC6A2ANPEP
SCHEMBL19787869 0.95 DPP3 (0.69) DPP3OPRM1RENSLC6A2ANPEP
SCHEMBL31090175 0.95 DPP3 (0.77) DPP3OPRM1SLC6A2ANPEPLNPEP
SCHEMBL30023454 0.91 DPP3 (0.64) DPP3OPRM1SLC6A2KISS1R
SCHEMBL29993706 0.91 DPP3 (0.68) DPP3RENSLC6A2
SCHEMBL30392261 0.90 DPP3 (0.61) DPP3OPRM1SLC6A2KISS1R
SCHEMBL31402672 0.90 KISS1R (0.63) DPP3OPRM1RENSLC6A2KISS1R
SCHEMBL31402666 0.88 AGTR2 (0.61) DPP3OPRM1RENSLC6A2KISS1R
SCHEMBL30953538 0.88 DPP3 (0.62) DPP3OPRM1RENSLC6A2
SCHEMBL30424046 0.88 DPP3 (0.67) DPP3OPRM1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687942-A1 DPP3 INHIBITOR FOR MYOCARDIAL PROTECTION AND PREVENTION OF MYOCARDIAL INJURY IN CRITICALLY ILL PATIENTS WITH BLOOD PRESSURE DECLINE 4TEEN4 Pharmaceuticals GmbH (DE) 2026-02-11 — — EP claimed
EP-4633659-A1 DPP3 INHIBITOR FOR IMPROVEMENT OF PULMONARY FUNCTION IN CRITICALLY ILL PATIENTS 4TEEN4 Pharmaceuticals GmbH (DE) 2025-10-22 — — EP claimed
WO-2024200862-A1 DPP3 INHIBITOR FOR MYOCARDIAL PROTECTION AND PREVENTION OF MYOCARDIAL INJURY IN CRITICALLY ILL PATIENTS WITH BLOOD PRESSURE DECLINE 4TEEN4 Pharmaceuticals GmbH (DE) 2024-10-03 — — WO claimed
WO-2024126793-A1 DPP3 INHIBITOR FOR IMPROVEMENT OF PULMONARY FUNCTION IN CRITICALLY ILL PATIENTS 4TEEN4 Pharmaceuticals GmbH (DE) 2024-06-20 — — WO claimed
US-20260083672-A1 FORMULATIONS AND DOSAGE AMOUNTS FOR ADMINISTERING AN ANTI-DPP3 ANTIBODY OR FRAGMENT THEREOF TO HUMANS 4TEEN4 Pharmaceuticals GmbH (DE) 2026-03-26 — — US disclosed
EP-4687942-A1 DPP3 INHIBITOR FOR MYOCARDIAL PROTECTION AND PREVENTION OF MYOCARDIAL INJURY IN CRITICALLY ILL PATIENTS WITH BLOOD PRESSURE DECLINE 4TEEN4 Pharmaceuticals GmbH (DE) 2026-02-11 — — EP disclosed
EP-4633659-A1 DPP3 INHIBITOR FOR IMPROVEMENT OF PULMONARY FUNCTION IN CRITICALLY ILL PATIENTS 4TEEN4 Pharmaceuticals GmbH (DE) 2025-10-22 — — EP disclosed
EP-4527458-A2 DPP3 BINDER DIRECTED TO AND BINDING TO SPECIFIC DPP3-EPITOPES AND ITS USE IN THE PREVENTION OR TREATMENT OF DISEASES / ACUTE CONDITIONS THAT ARE ASSOCIATED WITH OXIDATIVE STRESS 4TEEN4 Pharmaceuticals GmbH (DE) 2025-03-26 — — EP disclosed
WO-2025050228-A1 PHARMACEUTICAL COMPOSITION COMPRISING A PEPTIDE OR A COMBINATION OF PEPTIDES AGONISTIC TO THE MAS, AT1 AND AT2 RECEPTORS PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) 2025-03-13 — — WO disclosed
US-20240385197-A1 METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS 4TEEN4 Pharmaceuticals GmbH (DE) 2024-11-21 — — US disclosed
CN-118791621-A DPP3 binding agents directed against and binding to specific DPP3 epitopes and their use in the prevention or treatment of diseases/acute conditions associated with oxidative stress 4TEEN4制药有限公司 2024-10-18 — — CN disclosed
WO-2024200862-A1 DPP3 INHIBITOR FOR MYOCARDIAL PROTECTION AND PREVENTION OF MYOCARDIAL INJURY IN CRITICALLY ILL PATIENTS WITH BLOOD PRESSURE DECLINE 4TEEN4 Pharmaceuticals GmbH (DE) 2024-10-03 — — WO disclosed
WO-2024126793-A1 DPP3 INHIBITOR FOR IMPROVEMENT OF PULMONARY FUNCTION IN CRITICALLY ILL PATIENTS 4TEEN4 Pharmaceuticals GmbH (DE) 2024-06-20 — — WO disclosed
US-20230295344-A1 DPP3 BINDER DIRECTED TO AND BINDING TO SPECIFIC DPP3-EPITOPES AND ITS USE IN THE PREVENTION OR TREATMENT OF DISEASES/ACUTE CONDITIONS THAT ARE ASSOCIATED WITH OXIDATIVE STRESS 4TEEN4 Pharmaceuticals GmbH (DE) 2023-09-21 — — US disclosed
US-11726094-B2 Methods for determining DPP3 and therapeutic methods 4TEEN4 Pharmaceuticals GmbH (DE) 2023-08-15 — — US disclosed
US-20230213519-A1 DPP3 IN PATIENTS INFECTED WITH CORONAVIRUS 4TEEN4 Pharmaceuticals GmbH (DE) 2023-07-06 — — US disclosed
CN-115769076-A DPP3 in patients infected with coronaviruses 4TEEN4制药有限公司 2023-03-07 — — CN disclosed
EP-4121763-A1 DPP3 IN PATIENTS INFECTED WITH CORONAVIRUS 4TEEN4 Pharmaceuticals GmbH (DE) 2023-01-25 — — EP disclosed
US-11530276-B2 DPP3 binder directed to and binding to specific DPP3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress 4TEEN4 Pharmaceuticals GmbH (DE) 2022-12-20 — — US disclosed
US-20220226446-A1 NEUROTOXIN COMPOSITIONS FOR USE IN IMPROVING LUNG FUNCTION BONTI INC (US) 2022-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083672-A1 FORMULATIONS AND DOSAGE AMOUNTS FOR ADMINISTERING AN ANTI-DPP3 ANTIBODY OR FRAGMENT THEREOF TO HUMANS DPP3, DPP4, TREH DPP3 1/4885OPRM1 1613/4885REN 333/4885
US-11530276-B2 DPP3 binder directed to and binding to specific DPP3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress DPP3, DPP4, DPP7 DPP3 1/4885OPRM1 3459/4885REN 226/4885
US-20230213519-A1 DPP3 IN PATIENTS INFECTED WITH CORONAVIRUS DPP3, DPP4, DPP7 DPP3 1/4885OPRM1 2046/4885REN 261/4885
US-20240385197-A1 METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS DPP3, DPP4, DPP7 DPP3 1/4885OPRM1 2816/4885REN 263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback