Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577442 | 1.00 | EPHX2 (0.62) | EPHX2MTORLMNAIDO1RAB9A | |
| SCHEMBL14434568 | 0.90 | LMNA (0.73) | EPHX2MTORLMNARAB9AROCK2 | |
| SCHEMBL8177075 | 0.86 | EGFR (0.65) | MTORRAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL14433810 | 0.84 | RAB9A (0.78) | EPHX2MTORLMNARAB9AMAPT | |
| SCHEMBL8176987 | 0.83 | LMNA (0.71) | EPHX2MTORLMNARAB9AKMT2A | |
| SCHEMBL29804195 | 0.81 | LMNA (0.66) | LMNARAB9AROCK2MAPTKMT2A | |
| SCHEMBL28577264 | 0.81 | LMNA (0.66) | LMNARAB9AROCK2MAPTKMT2A | |
| SCHEMBL11920201 | 0.78 | SRC (0.65) | RAB9AMAPTNPC1POLBEGFR | |
| SCHEMBL11613865 | 0.77 | NAMPT (0.82) | MTORLMNARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL881870 | 0.76 | EPHX2 (0.60) | EPHX2MTORLMNARAB9AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961081-B | Bibenzamide urea compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-13 | — | — | CN | disclosed |