Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808310 | 0.98 | ALOX15 (0.40) | ALOX15CRBNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29808205 | 0.95 | ALOX15 (0.42) | ALOX15CRBNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27218791 | 0.80 | RAB9A (0.48) | ALOX15NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL31494451 | 0.77 | RAB9A (0.48) | ALOX15NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29808161 | 0.74 | ALOX15 (0.43) | ALOX15NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27218745 | 0.74 | RAB9A (0.50) | ALOX15NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29807808 | 0.72 | TSHR (0.61) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL31494372 | 0.71 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29808248 | 0.71 | NPC1 (0.46) | ALOX15NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL19193199 | 0.70 | POLB (0.44) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | GBIOTECH S.À.R.L. (CH) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | FFAR2, FFAR1, FFAR3 | ALOX15 111/4885CRBN 4797/4885NPC1 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.