Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.47 |
| ▸ | CTSD | P07339 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720815 | 0.92 | BACE1 (0.46) | BACE1CTSDOPRD1BACE2 | |
| SCHEMBL7745414 | 0.90 | BACE1 (0.42) | BACE1CTSDOPRD1 | |
| SCHEMBL29362216 | 0.90 | BACE1 (0.42) | BACE1CTSDOPRD1 | |
| SCHEMBL30555686 | 0.89 | DPP4 (0.45) | BACE1CTSDOPRD1DPP4DPP8 | |
| SCHEMBL31410666 | 0.87 | OPRD1 (0.42) | BACE1CTSDOPRD1OPRM1OPRK1 | |
| SCHEMBL31410681 | 0.86 | BACE1 (0.44) | BACE1CTSDOPRD1OPRM1OPRK1 | |
| SCHEMBL31410885 | 0.85 | GLO1 (0.42) | BACE1CTSDOPRD1 | |
| SCHEMBL30563243 | 0.85 | DPP4 (0.45) | BACE1CTSDOPRD1DPP4DPP8 | |
| SCHEMBL6049342 | 0.84 | BACE1 (0.48) | BACE1CTSDBACE2 | |
| SCHEMBL6049343 | 0.84 | BACE1 (0.48) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796123-A | Self-assembled peptide nano preparation with anti-hepatic fibrosis function and preparation method and application thereof | 安徽医科大学 | 2022-07-29 | — | — | CN | claimed |
| US-11667694-B2 | Therapeutic uses of fibrinogen gamma prime variants | FIBRIANT B.V. (NL) | 2023-06-06 | — | — | US | disclosed |
| CN-114796123-A | Self-assembled peptide nano preparation with anti-hepatic fibrosis function and preparation method and application thereof | 安徽医科大学 | 2022-07-29 | — | — | CN | disclosed |