Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802853 | 1.00 | ADRB2 (0.42) | ADRB2ADRB1PGRCYP1A2CYP3A4 | |
| SCHEMBL1240016 | 1.00 | ADRB2 (0.42) | ADRB2ADRB1PGRCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28802793 | 0.98 | ADRB2 (0.41) | ADRB2ADRB1PGRCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3703483 | 0.98 | ADRB2 (0.41) | ADRB2ADRB1PGRCYP1A2CYP3A4 | |
| SCHEMBL16649615 | 0.85 | TRPV4 (0.48) | ADRB2ADRB1PIK3CDABL1EGFR | |
| SCHEMBL22495734 | 0.85 | TRPV4 (0.48) | ADRB2ADRB1PIK3CDABL1EGFR | |
| SCHEMBL28802774 | 0.85 | TRPV4 (0.48) | ADRB2ADRB1PIK3CDABL1EGFR | |
| SCHEMBL879123 | 0.85 | PGR (0.43) | ADRB2ADRB1PGRCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28803022 | 0.84 | TRPV4 (0.47) | ADRB2ADRB1PIK3CDABL1EGFR | |
| SCHEMBL30892077 | 0.82 | CYP11B1 (0.45) | ADRB2ADRB1PGRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835687-B | AhR inhibitors | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114835687-A | AhR inhibitors | 重庆华森制药股份有限公司 | 2022-08-02 | — | — | CN | disclosed |