Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325982 | 1.00 | PRMT6 (0.68) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| Hydrochloric Acid SCHEMBL9023633 | 0.98 | PRMT6 (0.66) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| SCHEMBL20209847 | 0.98 | PRMT6 (0.66) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| Hydrochloric Acid SCHEMBL10665202 | 0.96 | PRMT6 (0.64) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| SCHEMBL20209838 | 0.96 | PRMT6 (0.62) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| SCHEMBL11339852 | 0.88 | PRMT6 (0.78) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| SCHEMBL11192726 | 0.88 | PRMT6 (0.78) | PRMT6SMN1; SMN2ALDH1A1TDP1HRH3 | |
| Hydrochloric Acid SCHEMBL9024937 | 0.82 | MC4R (0.66) | PRMT6ALDH1A1HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9024294 | 0.82 | NCF1 (0.69) | PRMT6SMN1; SMN2ALDH1A1HRH3KDM4E | |
| SCHEMBL6057453 | 0.81 | HRH3 (0.77) | SMN1; SMN2ALDH1A1HRH3CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805341-B | Aromatic heterocyclic compound, and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |