SCHEMBL29809458

SCHEMBL29809458

c1cc(-c2ccncc2)c2sc(-c3ccncc3)cc2c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.48
GSK3B P49841 8/20 0.46
CDK2 P24941 4/20 0.46
CDC7 O00311 4/20 0.44
DBF4 Q9UBU7 4/20 0.44
PRKCI P41743 3/20 0.39
TNF P01375 1/20 0.39
MAPK11 Q15759 1/20 0.38
MAPK14 Q16539 1/20 0.38
PIK3CD O00329 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29212886 0.83 CYP1A1 (0.47) TNF
SCHEMBL29936699 0.83 CYP1A1 (0.47) TNF
SCHEMBL29809418 0.81 CYP11B1 (0.49)
SCHEMBL2923179 0.79 TDO2 (0.39) PDE10AGSK3BCDK2CDC7DBF4
SCHEMBL2925835 0.78 PDE10A (0.37) PDE10AGSK3BCDK2CDC7DBF4
SCHEMBL2176875 0.77 CA2 (0.57) PDE10ACDK2
SCHEMBL23264005 0.76 CDC7 (0.45) GSK3BCDK2CDC7DBF4PRKCI
SCHEMBL25165540 0.75 CDC7 (0.44) GSK3BCDK2CDC7DBF4PIK3CD
SCHEMBL388931 0.73 CYP2A6 (0.42) PDE10ATNFMAPK11MAPK14PIK3CD
SCHEMBL31227788 0.72 CDC7 (0.42) GSK3BCDK2CDC7DBF4PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734451-B Semiconductor material, preparation method thereof and organic light-emitting diode 北京大学深圳研究生院 2022-07-22 CN disclosed