Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 17/20 | 0.80 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29810180 | 0.99 | TPH1 (0.80) | TPH1S1PR1S1PR5TP53MITF | |
| SCHEMBL20777159 | 0.89 | TPH1 (1.00) | TPH1S1PR1TP53NPC1RAB9A | |
| SCHEMBL20777161 | 0.89 | TPH1 (1.00) | TPH1S1PR1TP53NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL22150732 | 0.88 | TPH1 (1.00) | TPH1S1PR1TP53NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL22150736 | 0.88 | TPH1 (1.00) | TPH1S1PR1TP53NPC1RAB9A | |
| SCHEMBL29810083 | 0.87 | TPH1 (0.73) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810128 | 0.86 | TPH1 (0.74) | TPH1 | |
| SCHEMBL29810085 | 0.85 | TPH1 (0.78) | TPH1S1PR1S1PR5 | |
| SCHEMBL20777117 | 0.85 | TPH1 (0.81) | TPH1 | |
| SCHEMBL20777116 | 0.85 | TPH1 (0.81) | TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |