Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 16/20 | 0.73 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29810128 | 0.99 | TPH1 (0.74) | TPH1SMPD1PPARDPPARAPPARG | |
| SCHEMBL20777116 | 0.88 | TPH1 (0.81) | TPH1 | |
| SCHEMBL20777117 | 0.88 | TPH1 (0.81) | TPH1 | |
| SCHEMBL29810052 | 0.87 | TPH1 (0.80) | TPH1 | |
| SCHEMBL29810105 | 0.87 | TPH1 (0.76) | TPH1 | |
| Hydrochloric Acid SCHEMBL22150783 | 0.86 | TPH1 (0.82) | TPH1 | |
| Hydrochloric Acid SCHEMBL22150784 | 0.86 | TPH1 (0.82) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810180 | 0.86 | TPH1 (0.80) | TPH1 | |
| Hydrochloric Acid SCHEMBL29810124 | 0.85 | TPH1 (0.77) | TPH1 | |
| SCHEMBL22449244 | 0.85 | PPARG (0.57) | TPH1SMPD1PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |