Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 18/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29810112 | 0.99 | TPH1 (0.73) | TPH1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL29810064 | 0.96 | TPH1 (0.79) | TPH1MAPTLMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29810119 | 0.95 | TPH1 (0.79) | TPH1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL29810061 | 0.93 | TPH1 (0.72) | TPH1MAPTLMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL29810135 | 0.93 | TPH1 (0.73) | TPH1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL29810079 | 0.86 | TPH1 (0.78) | TPH1MAPTNPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL29810131 | 0.85 | TPH1 (0.79) | TPH1MAPTNPC1TP53RAB9A | |
| SCHEMBL20777159 | 0.85 | TPH1 (1.00) | TPH1MAPTMEN1NPC1TP53 | |
| SCHEMBL20777161 | 0.85 | TPH1 (1.00) | TPH1MAPTMEN1NPC1TP53 | |
| SCHEMBL29810156 | 0.84 | TPH1 (0.82) | TPH1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |