Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 16/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29810131 | 0.99 | TPH1 (0.79) | TPH1NPC1RAB9ATP53NFKB1 | |
| SCHEMBL29810098 | 0.93 | TPH1 (0.84) | TPH1NPC1RAB9ATP53NFKB1 | |
| SCHEMBL29810156 | 0.92 | TPH1 (0.82) | TPH1CYP3A4MAPTCYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL29810114 | 0.92 | TPH1 (0.85) | TPH1NPC1RAB9ATP53NFKB1 | |
| Hydrochloric Acid SCHEMBL29810149 | 0.91 | TPH1 (0.83) | TPH1CYP3A4MAPTCYP2C19KMT2A | |
| SCHEMBL20777159 | 0.88 | TPH1 (1.00) | TPH1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL20777161 | 0.88 | TPH1 (1.00) | TPH1NPC1RAB9ATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL22150736 | 0.87 | TPH1 (1.00) | TPH1NPC1RAB9ATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL22150732 | 0.87 | TPH1 (1.00) | TPH1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL29810056 | 0.86 | TPH1 (0.73) | TPH1NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |