Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.56 |
| ▸ | TPH1 | P17752 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448969 | 0.89 | TPH1 (0.58) | PPARGTPH1PPARDPPARA | |
| SCHEMBL22449171 | 0.88 | TPH1 (0.56) | PPARGSMPD1TPH1 | |
| SCHEMBL15037260 | 0.85 | GPR132 (0.55) | PPARGSMPD1PPARDPPARAGPR34 | |
| SCHEMBL22449147 | 0.85 | S1PR1 (0.59) | PPARGTPH1PPARDPPARAFFAR1 | |
| SCHEMBL29810083 | 0.85 | TPH1 (0.73) | PPARGSMPD1TPH1PPARDPPARA | |
| SCHEMBL22449256 | 0.84 | TPH1 (0.57) | PPARGTPH1PPARDPPARA | |
| Hydrochloric Acid SCHEMBL29810128 | 0.84 | TPH1 (0.74) | PPARGSMPD1TPH1PPARDPPARA | |
| SCHEMBL8760872 | 0.84 | PPARG (0.67) | PPARGPPARDPPARAGPR34 | |
| SCHEMBL2035189 | 0.84 | PPARG (0.67) | PPARGPPARDPPARAGPR34 | |
| SCHEMBL2030203 | 0.84 | PPARG (0.67) | PPARGPPARDPPARAGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |