Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235666 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL28304227 | 0.78 | TDP1 (0.41) | ALDH1A1TDP1PIN1CYP3A4MAPT | |
| SCHEMBL30399809 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL4719832 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL14333666 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL16909314 | 0.76 | HTT (0.39) | ALDH1A1TDP1KDM4EMAPTPKM | |
| SCHEMBL1100650 | 0.76 | PIN1 (0.50) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL17222837 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL221671 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1PIN1KDM4ECYP3A4 | |
| SCHEMBL29811740 | 0.76 | PIN1 (0.50) | ALDH1A1TDP1PIN1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034104-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |