Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16909314 | 0.79 | HTT (0.39) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL16235666 | 0.78 | ALDH1A1 (0.41) | TDP1MAPTALDH1A1LMNAPKM | |
| SCHEMBL29812036 | 0.78 | ALDH1A1 (0.41) | TDP1MAPTALDH1A1LMNAPKM | |
| SCHEMBL31030195 | 0.76 | POLB (0.45) | TDP1TSHRALDH1A1POLBLMNA | |
| SCHEMBL28874061 | 0.76 | PIK3CB (0.39) | POLBLMNAL3MBTL1CA12CA1 | |
| SCHEMBL30893421 | 0.75 | TDP1 (0.48) | TDP1TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL8781226 | 0.75 | TDP1 (0.48) | TDP1TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL5252473 | 0.74 | TDP1 (0.48) | TDP1TSHRMAPTALDH1A1MEN1 | |
| SCHEMBL11632172 | 0.73 | PKM (0.43) | TDP1MAPTALDH1A1MEN1POLB | |
| SCHEMBL11797396 | 0.73 | TDP1 (0.47) | TDP1TSHRMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956927-A | Benzimidazoles derivative, preparation method and its in application pharmaceutically | 北京诺诚健华医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |