Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089594 | 1.00 | DRD2 (0.45) | DRD2DRD3PARP1IKBKBNOS3 | |
| SCHEMBL23114442 | 0.83 | MAP4K4 (0.50) | DRD2DRD3PARP1IKBKBMAP4K4 | |
| SCHEMBL12090447 | 0.83 | MAP4K4 (0.50) | DRD2DRD3PARP1IKBKBMAP4K4 | |
| SCHEMBL29645408 | 0.81 | HTR1A (0.48) | DRD2PARP1NOS3NOS1NOS2 | |
| SCHEMBL5338979 | 0.81 | HTR1A (0.48) | DRD2PARP1NOS3NOS1NOS2 | |
| SCHEMBL17896786 | 0.80 | PARP1 (0.55) | DRD2DRD3PARP1IKBKBMAP4K4 | |
| SCHEMBL31715424 | 0.80 | HTR2A (0.46) | DRD2MAP4K4HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL31655491 | 0.80 | HTR1A (0.47) | DRD2PARP1NOS3NOS1NOS2 | |
| SCHEMBL23103376 | 0.79 | DRD2 (0.43) | DRD2DRD3PARP1IKBKBPRMT5 | |
| SCHEMBL23467570 | 0.79 | DRD2 (0.43) | DRD2DRD3PARP1PRMT5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874700-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114945366-B | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |