Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759431 | 0.74 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL14185947 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2ANR4A2LMNA | |
| SCHEMBL9520813 | 0.70 | KDM4E (0.60) | ALDH1A1KDM4EHTT | |
| SCHEMBL14665132 | 0.70 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL13896419 | 0.70 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL11921550 | 0.70 | RAB9A (0.69) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9517585 | 0.70 | KDM4E (0.59) | ALDH1A1KDM4EHTT | |
| SCHEMBL14745414 | 0.69 | LMNA (0.71) | ALDH1A1SMN1; SMN2KMT2ANR4A2LMNA | |
| SCHEMBL14828742 | 0.68 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL1558956 | 0.68 | POLB (0.68) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845717-A | Treatment of schizophrenia disorders using combination therapy | 剑桥认知有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114845717-A | Treatment of schizophrenia disorders using combination therapy | 剑桥认知有限公司 | 2022-08-02 | — | — | CN | disclosed |