Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291193 | 0.80 | POLB (0.60) | HIF1APOLBMAPK1TSHRCYP2D6 | |
| SCHEMBL13060284 | 0.78 | POLB (0.48) | HIF1APOLBMAPK1TSHRCYP2D6 | |
| SCHEMBL13003576 | 0.76 | ITGA4 (0.47) | HIF1APOLBMAPK1TSHRCYP2D6 | |
| SCHEMBL28044796 | 0.69 | RECQL (0.48) | HIF1ATSHRCYP2D6CA12CA2 | |
| SCHEMBL13334635 | 0.68 | KMT2A (0.42) | POLB | |
| SCHEMBL11977390 | 0.67 | MAPK1 (0.63) | HIF1APOLBMAPK1TSHRCYP2D6 | |
| SCHEMBL28044791 | 0.67 | HIF1A (0.59) | HIF1ATSHRCYP2D6CA12CA2 | |
| SCHEMBL3293164 | 0.67 | MEN1 (0.37) | HIF1ATSHRCA12CA2CA9 | |
| SCHEMBL11209719 | 0.66 | SMN1; SMN2 (0.54) | TSHRCA12CA2CA9CA1 | |
| SCHEMBL32665522 | 0.66 | TSHR (0.53) | HIF1ATSHRCYP2D6CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226231-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE (FR) | 2023-07-20 | — | — | US | claimed |
| EP-4168054-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | Universite d'Aix Marseille (FR) | 2023-04-26 | — | — | EP | claimed |
| US-20230226231-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE (FR) | 2023-07-20 | — | — | US | disclosed |
| EP-4168054-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | Universite d'Aix Marseille (FR) | 2023-04-26 | — | — | EP | disclosed |
| US-11427648-B2 | Anti-CD146 antibodies and uses thereof | UNIVERSITE D'AIX-MARSEILLE (FR) | 2022-08-30 | — | — | US | disclosed |