Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060284 | 0.89 | POLB (0.48) | POLBMAPK1PKMMPOTSHR | |
| SCHEMBL11977390 | 0.84 | MAPK1 (0.63) | POLBMAPK1PKMMPOTSHR | |
| SCHEMBL13003576 | 0.83 | ITGA4 (0.47) | POLBMAPK1TSHRCYP2D6HIF1A | |
| SCHEMBL29816787 | 0.80 | HIF1A (0.41) | POLBMAPK1PKMMPOTSHR | |
| SCHEMBL6435315 | 0.75 | PKM (0.96) | POLBMAPK1PKMMPOTSHR | |
| SCHEMBL7744629 | 0.74 | POLB (0.62) | POLBMAPK1PKMMPOTSHR | |
| SCHEMBL6234672 | 0.74 | POLB (0.61) | POLBMAPK1PKMMPOTSHR | |
| SCHEMBL11574253 | 0.73 | TSHR (0.69) | PKMMPOTSHRCYP2D6HIF1A | |
| SCHEMBL27537010 | 0.73 | TSHR (0.69) | PKMMPOTSHRCYP2D6HIF1A | |
| SCHEMBL21417821 | 0.73 | POLB (0.60) | POLBMAPK1PKMMPOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334320-B2 | Methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-12-18 | — | — | US | disclosed |
| US-8334320-B2 | Methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-12-18 | — | — | US | disclosed |