Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493267 | 0.87 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1NCF1POLBCA2 | |
| SCHEMBL2431131 | 0.87 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1NCF1POLBCA2 | |
| SCHEMBL13736051 | 0.85 | ALDH1A1 (0.42) | ALDH1A1PRMT6MAPTKDM4EGAA | |
| SCHEMBL29818145 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EGAARAD52 | |
| SCHEMBL27609222 | 0.81 | HTR6 (0.45) | ALDH1A1OPRL1MAPTGAASMN1; SMN2 | |
| SCHEMBL1238877 | 0.81 | NCF1 (0.46) | ALDH1A1NCF1MAPTKDM4EGAA | |
| SCHEMBL4485868 | 0.79 | MAPT (0.61) | ALDH1A1L3MBTL1NCF1POLBCA2 | |
| SCHEMBL29493256 | 0.79 | MAPT (0.45) | ALDH1A1L3MBTL1NCF1POLBCA2 | |
| SCHEMBL18656450 | 0.79 | NCF1 (0.35) | ALDH1A1NCF1POLBMAPTKDM4E | |
| SCHEMBL9300032 | 0.78 | MAPT (0.60) | ALDH1A1L3MBTL1NCF1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |