Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 13/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836828 | 0.93 | DGAT1 (0.52) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29818071 | 0.91 | DGAT1 (0.51) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29818223 | 0.91 | MEN1 (0.52) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29836774 | 0.90 | ALDH1A1 (0.50) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29836789 | 0.90 | MEN1 (0.53) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29817948 | 0.85 | NPC1 (0.68) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29818190 | 0.80 | DGAT1 (0.56) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29818048 | 0.79 | NPC1 (0.71) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29818191 | 0.79 | NPC1 (0.62) | NPC1ALDH1A1LMNATP53MAPT | |
| SCHEMBL29818159 | 0.79 | DGAT1 (0.52) | NPC1ALDH1A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |