Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836789 | 0.99 | MEN1 (0.53) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29818071 | 0.98 | DGAT1 (0.51) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29836828 | 0.96 | DGAT1 (0.52) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29818215 | 0.91 | NPC1 (0.53) | DGAT1SMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL29836774 | 0.89 | ALDH1A1 (0.50) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29818190 | 0.83 | DGAT1 (0.56) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29817936 | 0.82 | MAPT (0.66) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29818048 | 0.82 | NPC1 (0.71) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29818159 | 0.81 | DGAT1 (0.52) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29818284 | 0.80 | DGAT1 (0.53) | MEN1KMT2ADGAT1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |