Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2973729 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL4225555 | 0.82 | HTT (0.40) | ALDH1A1KDM4EHPGDGAAHTT | |
| SCHEMBL13221207 | 0.81 | MAPK1 (0.50) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL2970846 | 0.79 | MAPK1 (0.48) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL2972073 | 0.79 | MAPK1 (0.48) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL8325573 | 0.70 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL8227587 | 0.70 | MAPK1 (0.70) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL2982074 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL13221209 | 0.69 | MAPK1 (0.51) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL344481 | 0.69 | KDM4E (0.53) | ALDH1A1KDM4EHPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776107-B2 | Aminoindolizines, dyeing composition comprising at least one aminoindolizine, methods and uses thereof | L'OREAL S.A. (FR) | 2010-08-17 | — | — | US | disclosed |
| US-7776107-B2 | Aminoindolizines, dyeing composition comprising at least one aminoindolizine, methods and uses thereof | L'OREAL S.A. (FR) | 2010-08-17 | — | — | US | disclosed |
| US-20090235467-A1 | NEW AMINOINDOLIZINES, DYEING COMPOSITION COMPRISING AT LEAST ONE AMINOINDOLIZINE, METHODS AND USES THEREOF | L'OREAL S.A. (FR) | 2009-09-24 | — | — | US | disclosed |
| US-20090235467-A1 | NEW AMINOINDOLIZINES, DYEING COMPOSITION COMPRISING AT LEAST ONE AMINOINDOLIZINE, METHODS AND USES THEREOF | L'OREAL S.A. (FR) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090235467-A1 | NEW AMINOINDOLIZINES, DYEING COMPOSITION COMPRISING AT LEAST ONE AMINOINDOLIZINE, METHODS AND USES THEREOF | KRT18, AADAT, ALAD | ALDH1A1 723/4885KDM4E 977/4885HPGD 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.