Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.42 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968223 | 0.82 | TK1 (0.44) | TK1RNASE1NT5MTK2DHFR | |
| SCHEMBL9978645 | 0.82 | TK1 (0.44) | TK1RNASE1NT5MTK2DHFR | |
| SCHEMBL23086299 | 0.82 | TK1 (0.42) | TK1RNASE1NT5MTK2DHFR | |
| SCHEMBL27976013 | 0.82 | TK1 (0.42) | TK1RNASE1NT5MTK2DHFR | |
| SCHEMBL9978644 | 0.81 | TK1 (0.43) | TK1RNASE1NT5MTK2DHFR | |
| SCHEMBL14968221 | 0.81 | TK1 (0.43) | TK1RNASE1NT5MTK2DHFR | |
| SCHEMBL19660825 | 0.81 | TK1 (0.45) | TK1RNASE1TK2 | |
| SCHEMBL409820 | 0.80 | RNASE1 (0.50) | TK1RNASE1TK2 | |
| SCHEMBL19953995 | 0.80 | TK1 (0.44) | TK1RNASE1TK2 | |
| SCHEMBL441127 | 0.80 | RNASE1 (0.50) | TK1RNASE1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022230954-A1 | METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND | 日本新薬株式会社 | 2022-11-03 | — | — | WO | disclosed |
| CN-114981281-A | Method for producing oligonucleotide compound | 日本新药株式会社 | 2022-08-30 | — | — | CN | disclosed |