Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | RAMP3 | O60896 | 15/20 | 0.52 |
| ▸ | CALCR | P30988 | 15/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29827592 | 0.99 | RAMP3 (0.53) | KEAP1RAMP3CALCRPTPN1 | |
| SCHEMBL30495774 | 0.86 | RAMP3 (0.54) | RAMP3CALCR | |
| SCHEMBL9058997 | 0.85 | RAMP3 (0.56) | KEAP1RAMP3CALCR | |
| SCHEMBL9058995 | 0.85 | RAMP3 (0.56) | KEAP1RAMP3CALCR | |
| SCHEMBL8624738 | 0.84 | RAMP3 (0.51) | KEAP1RAMP3CALCR | |
| SCHEMBL8624746 | 0.84 | RAMP3 (0.51) | KEAP1RAMP3CALCR | |
| SCHEMBL8643257 | 0.83 | KEAP1 (0.47) | KEAP1RAMP3CALCR | |
| SCHEMBL8643264 | 0.83 | KEAP1 (0.47) | KEAP1RAMP3CALCR | |
| SCHEMBL29641591 | 0.83 | KEAP1 (0.49) | KEAP1RAMP3CALCRPTPN1 | |
| SCHEMBL8624366 | 0.83 | RAMP3 (0.50) | KEAP1RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773447-B | Application of ETGE polypeptide in preparation of medicines for treating multiple organ ischemia reperfusion injury | 华中科技大学同济医学院附属协和医院 | 2023-06-06 | — | — | CN | claimed |
| CN-114773447-A | Application of ETGE polypeptide in preparation of medicine for treating multiple organ ischemia reperfusion injury | 华中科技大学同济医学院附属协和医院 | 2022-07-22 | — | — | CN | claimed |
| CN-114773447-B | Application of ETGE polypeptide in preparation of medicines for treating multiple organ ischemia reperfusion injury | 华中科技大学同济医学院附属协和医院 | 2023-06-06 | — | — | CN | disclosed |
| CN-114773447-A | Application of ETGE polypeptide in preparation of medicine for treating multiple organ ischemia reperfusion injury | 华中科技大学同济医学院附属协和医院 | 2022-07-22 | — | — | CN | disclosed |