SCHEMBL29827592

C[C@H](N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O

nearest known ligand 0.53

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	15/20	0.53

▸	CALCR	P30988	15/20	0.53

▸	KEAP1	Q14145	2/20	0.52

▸	PTPN1	P18031	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29827555	0.99	KEAP1 (0.52)	RAMP3CALCRKEAP1PTPN1
SCHEMBL30495774	0.87	RAMP3 (0.54)	RAMP3CALCR
SCHEMBL9058995	0.86	RAMP3 (0.56)	RAMP3CALCRKEAP1
SCHEMBL9058997	0.86	RAMP3 (0.56)	RAMP3CALCRKEAP1
SCHEMBL29641613	0.84	KEAP1 (0.51)	RAMP3CALCRKEAP1PTPN1
SCHEMBL8624746	0.83	RAMP3 (0.51)	RAMP3CALCRKEAP1
SCHEMBL30099545	0.83	APLNR (0.48)	RAMP3CALCR
SCHEMBL8624738	0.83	RAMP3 (0.51)	RAMP3CALCRKEAP1
SCHEMBL10693642	0.83	RAMP3 (0.49)	RAMP3CALCR
SCHEMBL8643257	0.83	KEAP1 (0.47)	RAMP3CALCRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114773447-A	Application of ETGE polypeptide in preparation of medicine for treating multiple organ ischemia reperfusion injury	华中科技大学同济医学院附属协和医院	2022-07-22	—	—	CN	claimed
CN-114773447-A	Application of ETGE polypeptide in preparation of medicine for treating multiple organ ischemia reperfusion injury	华中科技大学同济医学院附属协和医院	2022-07-22	—	—	CN	disclosed