SCHEMBL29828705

SCHEMBL29828705

CC1(C)OC(=O)c2c(O)cccc2O1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.40
ALDH1A1 P00352 7/20 0.40
CYP3A4 P08684 4/20 0.40
CYP1A2 P05177 2/20 0.40
MAOA P21397 4/20 0.39
TXNRD1 Q16881 1/20 0.39
TXNRD3 Q86VQ6 1/20 0.39
TXNRD2 Q9NNW7 1/20 0.39
MAPT P10636 5/20 0.38
ALOX15 P16050 4/20 0.38
HSD17B10 Q99714 4/20 0.38
TDP1 Q9NUW8 4/20 0.38
MAOB P27338 3/20 0.38
LMNA P02545 3/20 0.38
TSHR P16473 3/20 0.38
HPGD P15428 3/20 0.38
MAPK1 P28482 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL620203 1.00 IDO1 (0.40) IDO1ALDH1A1CYP3A4CYP1A2MAOA
SCHEMBL26187073 0.80 PTPN1 (0.38) IDO1ALDH1A1MAOATXNRD1TXNRD3
SCHEMBL27379681 0.79 TSHR (0.38) ALDH1A1CYP3A4CYP1A2MAPTTDP1
SCHEMBL6824008 0.78 CA1 (0.42) IDO1ALDH1A1CYP3A4CYP1A2MAOA
SCHEMBL9155082 0.76 ALDH1A1 (0.57) ALDH1A1CYP3A4CYP1A2MAPTHSD17B10
SCHEMBL23655043 0.75 ALDH1A1 (0.48) IDO1ALDH1A1MAPTHSD17B10TDP1
SCHEMBL2863441 0.75 L3MBTL1 (0.42) ALDH1A1CYP3A4CYP1A2MAPTHSD17B10
SCHEMBL30645929 0.75 MEN1 (0.42) ALDH1A1CYP3A4CYP1A2MAOAMAPT
SCHEMBL15762161 0.75 MEN1 (0.42) ALDH1A1CYP3A4CYP1A2MAOAMAPT
SCHEMBL4371605 0.75 ALDH1A1 (0.37) ALDH1A1CYP3A4CYP1A2HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562016-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
CN-119907667-A Combination of macrocyclic CFTR modulators with CFTR corrector and/or CFTR potentiator 爱杜西亚药品有限公司 2025-04-29 CN disclosed
CN-113316568-B 2-Formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin 全球血液疗法股份有限公司 2024-11-08 CN disclosed
CN-108383858-B Derivatives of imidazothiadiazoles and imidazopyrazines for the treatment of platelet aggregation 百时美施贵宝公司 2024-09-20 CN disclosed
CN-113365992-B Process and intermediates for the preparation of Wo Sailuo torr 晶体制药独资有限公司 2024-05-28 CN disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
EP-4308575-A1 MACROCYCLES AS CFTR MODULATORS Idorsia Pharmaceuticals Ltd (CH) 2024-01-24 EP disclosed
WO-2023204308-A1 OXAZEPINE DERIVATIVE 帝人ファーマ株式会社 2023-10-26 WO disclosed
WO-2022194399-A1 MACROCYCLES AS CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2022-09-22 WO disclosed