Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 5/20 | 0.34 |
| ▸ | PAK4 | O96013 | 4/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017332 | 1.00 | CYP1A2 (0.38) | CYP1A2LMNATSHRHTTPOLB | |
| SCHEMBL29828959 | 0.88 | CYP3A4 (0.46) | CYP1A2LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL17017496 | 0.88 | CYP3A4 (0.46) | CYP1A2LMNATSHRALDH1A1CYP3A4 | |
| SCHEMBL29829259 | 0.86 | CYP1A2 (0.34) | CYP1A2LMNATSHRHTTALDH1A1 | |
| SCHEMBL17017500 | 0.86 | CYP1A2 (0.34) | CYP1A2LMNATSHRHTTALDH1A1 | |
| SCHEMBL17017493 | 0.82 | LMNA (0.42) | CYP1A2LMNATSHRHTTPOLB | |
| SCHEMBL19082950 | 0.81 | TSHR (0.39) | CYP1A2LMNATSHRHTTALDH1A1 | |
| SCHEMBL19065260 | 0.81 | CYP1A2 (0.37) | CYP1A2LMNATSHRHTTPOLB | |
| SCHEMBL29829728 | 0.81 | CYP1A2 (0.37) | CYP1A2LMNATSHRHTTPOLB | |
| SCHEMBL17017326 | 0.80 | CYP1A2 (0.59) | CYP1A2LMNATSHRHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274989-A9 | Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease | MITOKININ, INC. (US) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274989-A9 | Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease | NLN, NME4, COQ8A | CYP1A2 3043/4885LMNA 1287/4885TSHR 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.