SCHEMBL29831709

SCHEMBL29831709

c1ccc2c(c1)ccc1cc(-c3ccc(B4OCCO4)cc3)ccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.48
LIPG Q9Y5X9 2/20 0.48
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP1B1 Q16678 3/20 0.41
HIF1A Q16665 1/20 0.41
HPRT1 P00492 3/20 0.39
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
CYP1A1 P04798 2/20 0.35
CYP1A2 P05177 3/20 0.35
ERBB2 P04626 1/20 0.35
FYN P06241 1/20 0.35
MAOA P21397 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29846947 0.83 CYP11B1 (0.45) LPLLIPGALDH1A1HSD17B10CYP1B1
SCHEMBL13855205 0.82 HSD17B10 (0.48) LPLLIPGALDH1A1HSD17B10CYP1B1
SCHEMBL19106673 0.79 LIPG (0.78) LPLLIPGALDH1A1HSD17B10CYP1B1
SCHEMBL30008861 0.79 LIPG (0.78) LPLLIPGALDH1A1HSD17B10CYP1B1
SCHEMBL19335149 0.77 ALDH1A1 (0.30) ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL25412097 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL31171128 0.77 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL29832202 0.76 LPL (0.47) LPLLIPGALDH1A1HSD17B10TSHR
SCHEMBL2723055 0.75 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL3049189 0.75 LPL (0.53) LPLLIPGALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022173022-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAID COMPOUND 保土谷化学工業株式会社 2022-08-18 WO disclosed
WO-2022118910-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 保土谷化学工業株式会社 2022-06-09 WO disclosed