Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28855943 | 1.00 | GALR3 (0.35) | GALR3MAPTPOLBHTTALDH1A1 | |
| SCHEMBL1661075 | 0.85 | ALDH1A1 (0.33) | MAPTHTTALDH1A1LMNANPC1 | |
| SCHEMBL17801363 | 0.82 | ALDH1A1 (0.32) | MAPTHTTALDH1A1NPC1TP53 | |
| SCHEMBL20165931 | 0.82 | ALDH1A1 (0.35) | MAPTHTTALDH1A1NPC1TP53 | |
| SCHEMBL28855951 | 0.82 | ALDH1A1 (0.43) | MAPTHTTALDH1A1ATML3MBTL1 | |
| SCHEMBL21542864 | 0.77 | HTT (0.40) | GALR3MAPTHTTGAARAB9A | |
| SCHEMBL3951768 | 0.74 | MAPT (0.35) | MAPTHTTALDH1A1L3MBTL1NPC1 | |
| SCHEMBL1660845 | 0.71 | DGAT1 (0.36) | MAPTHTTALDH1A1RAB9ALMNA | |
| SCHEMBL1159252 | 0.71 | NOS3 (0.33) | MAPTPOLBALDH1A1RAB9ANPC1 | |
| SCHEMBL15109519 | 0.71 | MAPT (0.37) | MAPTHTTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989097-A | Preparation method of 5-amino-6-chloropyrimidine-4-carboxylic acid ethyl ester | 无锡捷化医药科技有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114989097-A | Preparation method of 5-amino-6-chloropyrimidine-4-carboxylic acid ethyl ester | 无锡捷化医药科技有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114989097-A | Preparation method of 5-amino-6-chloropyrimidine-4-carboxylic acid ethyl ester | 无锡捷化医药科技有限公司 | 2022-09-02 | — | — | CN | disclosed |