Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 3/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31575 | 0.89 | KDM4E (0.58) | KDM4EPKMCDC7DBF4ALDH1A1 | |
| SCHEMBL1417518 | 0.79 | KDM4E (0.49) | KDM4EPKMHDAC4HDAC6HDAC3 | |
| SCHEMBL20267761 | 0.78 | KDM4E (0.53) | KDM4EPKMALDH1A1KMT2AMAPT | |
| SCHEMBL27766706 | 0.78 | KDM4E (0.50) | KDM4EPKMCDC7DBF4TRPM8 | |
| SCHEMBL3333926 | 0.78 | ALDH1A1 (0.50) | KDM4EPKMCDC7DBF4ALDH1A1 | |
| SCHEMBL27634383 | 0.76 | KDM4E (0.55) | KDM4EPKMCDC7DBF4ALDH1A1 | |
| SCHEMBL30007138 | 0.76 | KDM4E (0.50) | KDM4EPKMALDH1A1CYP1A2NPC1 | |
| SCHEMBL29706037 | 0.74 | CDC7 (0.47) | KDM4EPKMCDC7DBF4TRPM8 | |
| SCHEMBL27656855 | 0.74 | KDM4E (0.51) | KDM4EPKMALDH1A1MAPTLMNA | |
| SCHEMBL11151547 | 0.74 | ALDH1A1 (0.54) | KDM4EPKMCDC7DBF4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115192711-A | Use of PDE7 inhibitors for the treatment of movement disorders | 奥默罗斯公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114984229-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | 奥默罗斯公司 | 2022-09-02 | — | — | CN | disclosed |