Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20267761 | 0.90 | KDM4E (0.53) | KDM4EPKMTSHRTDP1LMNA | |
| SCHEMBL31575 | 0.85 | KDM4E (0.58) | KDM4EPKMTDP1LMNANPC1 | |
| Formic Acid SCHEMBL31362863 | 0.85 | KDM4E (0.47) | KDM4EPKMTSHRL3MBTL1TDP1 | |
| SCHEMBL27634383 | 0.79 | KDM4E (0.55) | KDM4EPKMTDP1LMNANPC1 | |
| SCHEMBL27656855 | 0.76 | KDM4E (0.51) | KDM4EPKMTSHRLMNAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL29832016 | 0.76 | KDM4E (0.51) | KDM4EPKMTDP1LMNANPC1 | |
| SCHEMBL8751647 | 0.74 | PKM (0.53) | KDM4EPKML3MBTL1LMNANPC1 | |
| SCHEMBL31550097 | 0.74 | CASP3 (0.47) | KDM4EPKMTSHRTDP1NPC1 | |
| SCHEMBL25767003 | 0.73 | ALDH1A1 (0.42) | KDM4EPKMTSHRTDP1LMNA | |
| SCHEMBL27601586 | 0.73 | PKM (0.60) | KDM4EPKML3MBTL1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115192711-A | Use of PDE7 inhibitors for the treatment of movement disorders | 奥默罗斯公司 | 2022-10-18 | — | — | CN | disclosed |