Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 7/20 | 0.41 |
| ▸ | IGF1R | P08069 | 7/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 6/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30725504 | 0.90 | BCL6 (0.53) | BCL6INSRIGF1RALKCDK9 | |
| SCHEMBL29833039 | 0.78 | ALK (0.50) | INSRIGF1RALKCDK9CDK7 | |
| SCHEMBL29833319 | 0.78 | CDK7 (0.61) | BCL6INSRIGF1RALKCDK9 | |
| SCHEMBL13832208 | 0.78 | CDK7 (0.61) | BCL6INSRIGF1RALKCDK9 | |
| SCHEMBL29833158 | 0.77 | ROCK1 (0.41) | BCL6 | |
| SCHEMBL29833127 | 0.76 | INSR (0.53) | INSRIGF1RALKCDK9CDK7 | |
| SCHEMBL29833300 | 0.76 | INSR (0.61) | INSRIGF1RALKMAP4K1LRRK2 | |
| SCHEMBL29832994 | 0.74 | ALK (0.47) | INSRIGF1RALKCDK9CDK7 | |
| SCHEMBL29833217 | 0.74 | CDK1 (0.51) | INSRALKMAPK10MAPK9CDK2 | |
| SCHEMBL29833045 | 0.74 | BRD4 (0.53) | INSRIGF1RALKCDK9MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199589-A1 | PYRIMIDINE DERIVATIVES | 南京明德新药研发有限公司 | 2022-09-29 | — | — | WO | disclosed |