Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | INSR | P06213 | 3/20 | 0.56 |
| ▸ | IGF1R | P08069 | 3/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.56 |
| ▸ | BCL6 | P41182 | 1/20 | 0.56 |
| ▸ | MAP4K1 | Q92918 | 6/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832208 | 1.00 | CDK7 (0.61) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL30725504 | 0.87 | BCL6 (0.53) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL11916362 | 0.86 | CDK7 (0.60) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL29400320 | 0.86 | CDK7 (0.60) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL19313060 | 0.85 | CDK7 (0.59) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL26717249 | 0.85 | INSR (0.72) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL25056368 | 0.84 | IGF1R (0.46) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL14240702 | 0.84 | CDK7 (0.58) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL19669895 | 0.83 | CDK7 (0.66) | CDK7CDK9INSRIGF1RALK | |
| SCHEMBL23571876 | 0.82 | CDK7 (0.59) | CDK7CDK9INSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199589-A1 | PYRIMIDINE DERIVATIVES | 南京明德新药研发有限公司 | 2022-09-29 | — | — | WO | disclosed |