Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837164 | 0.90 | MEN1 (0.41) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL30758070 | 0.90 | AKT1 (0.47) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL12545455 | 0.88 | LMNA (0.39) | RAB9AHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29837172 | 0.88 | LMNA (0.39) | RAB9AHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL29837089 | 0.88 | LMNA (0.44) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL29837162 | 0.88 | MEN1 (0.44) | MEN1RAB9AKMT2AHDAC3HDAC1 | |
| SCHEMBL29837079 | 0.79 | MEN1 (0.37) | MEN1RAB9AKMT2AAKT1LMNA | |
| SCHEMBL29837260 | 0.78 | HDAC3 (0.36) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL29837189 | 0.77 | L3MBTL1 (0.41) | ALOX5MEN1RAB9AKMT2AHDAC3 | |
| SCHEMBL29837221 | 0.77 | RIPK1 (0.42) | ALOX5MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024011415-A1 | METHOD FOR PREPARING O-IODOPHENYL COMPOUND | 苏州大学 | 2024-01-18 | — | — | WO | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |