Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23632980 | 1.00 | DYRK1A (0.35) | DYRK1ADYRK1BMAT2AHCAR2KDM4C | |
| SCHEMBL31532076 | 0.77 | CDK4 (0.42) | MAT2AHSD17B10 | |
| SCHEMBL29837979 | 0.77 | ADORA2A (0.46) | HCAR2KDM4CMAPTESR2HSD17B10 | |
| SCHEMBL23638393 | 0.77 | ADORA2A (0.46) | HCAR2KDM4CMAPTESR2HSD17B10 | |
| SCHEMBL29861753 | 0.76 | PDK2 (0.39) | DYRK1ADYRK1B | |
| SCHEMBL15280148 | 0.74 | CDC7 (0.38) | DYRK1ADYRK1BHSD17B10 | |
| SCHEMBL31532055 | 0.74 | SIK2 (0.45) | DYRK1ADYRK1B | |
| SCHEMBL22612785 | 0.74 | SIK2 (0.45) | DYRK1ADYRK1B | |
| SCHEMBL29837916 | 0.74 | HTR1A (0.44) | MAT2AKDM4CMAPTPDE3BPDE3A | |
| SCHEMBL661610 | 0.73 | MEN1 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901664-B | Pyridone compounds and uses thereof | 南京再明医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114901664-A | Pyridone compound and application thereof | 江苏先声药业有限公司 | 2022-08-12 | — | — | CN | disclosed |