SCHEMBL29838947

SCHEMBL29838947

Cc1c(C(=O)Nc2ccc(C(=O)O)cc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 11/20 0.81
PPARA Q07869 3/20 0.81
CNR2 P34972 11/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838949 1.00 CNR1 (0.81) CNR1PPARACNR2
SCHEMBL29838948 0.90 CNR1 (0.79) CNR1PPARACNR2
SCHEMBL29838934 0.89 CNR1 (0.79) CNR1PPARACNR2
SCHEMBL29838890 0.89 CNR1 (0.73) CNR1PPARACNR2
SCHEMBL29838997 0.89 CNR2 (0.73) CNR1PPARACNR2
SCHEMBL29838931 0.88 CNR1 (0.75) CNR1PPARACNR2
SCHEMBL29838933 0.88 CNR2 (0.69) CNR1PPARACNR2
SCHEMBL4877355 0.87 CNR1 (0.77) CNR1PPARACNR2
SCHEMBL29838945 0.87 CNR2 (0.67) CNR1PPARACNR2
SCHEMBL29838939 0.87 CNR2 (0.68) CNR1PPARACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683672-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Beone Medicines I GmbH (CH) 2026-01-28 EP disclosed
US-20260007761-A1 Bioactive Conjugate, Preparation Method Therefor and Use Thereof BEONE MEDICINES I GMBH (CH) 2026-01-08 US disclosed
US-20250295798-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, AND MEDICAL USE THEREOF BEIGENE SWITZERLAND GMBH (CH) 2025-09-25 US disclosed
EP-4594327-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, AND MEDICAL USE THEREOF BeiGene Switzerland GmbH (CH) 2025-08-06 EP disclosed
WO-2025032556-A1 BIOACTIVE CONJUGATES, PREPARATION METHOD AND USE THEREOF BEIGENE SWITZERLAND GMBH (CH) 2025-02-13 WO disclosed
WO-2024194851-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF BEIGENE SWITZERLAND GMBH (CH) 2024-09-26 WO disclosed
WO-2024067811-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, AND MEDICAL USE THEREOF BEIGENE, LTD. (KY) 2024-04-04 WO disclosed
US-20230414775-A1 TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES REGENERON PHARMACEUTICALS, INC. 2023-12-28 US disclosed
WO-2022164239-A1 PYRAZOLE-CARBOXAMIDE DERIVATIVE COMPOUND AND USE THEREOF 주식회사 파미노젠 2022-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007761-A1 Bioactive Conjugate, Preparation Method Therefor and Use Thereof IGLV6-57, BCR, INCENP CNR1 3201/4885PPARA 3974/4885CNR2 3441/4885
US-20250295798-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, AND MEDICAL USE THEREOF SLC10A1, ERBB3, SLC10A2 CNR1 464/4885PPARA 322/4885CNR2 544/4885
US-20230414775-A1 TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES SDCBP, TEK, TEKT1 CNR1 4854/4885PPARA 4775/4885CNR2 4839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.