Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729546 | 1.00 | KMT2A (0.46) | KMT2AUSP2ALDH1A1HPGDKCNK3 | |
| SCHEMBL22729857 | 0.87 | ALDH1A1 (0.45) | KMT2AALDH1A1HPGDBRPF1RAB9A | |
| SCHEMBL22729483 | 0.84 | RAB9A (0.48) | KMT2AALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL22729577 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDRAB9AGAAHTT | |
| SCHEMBL29839295 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDRAB9AGAAHTT | |
| SCHEMBL29839376 | 0.82 | KDM4E (0.41) | KMT2AALDH1A1HPGDPDE10ABRPF1 | |
| SCHEMBL22729653 | 0.82 | KDM4E (0.41) | KMT2AALDH1A1HPGDPDE10ABRPF1 | |
| SCHEMBL22729472 | 0.81 | RAB9A (0.55) | KMT2AUSP2ALDH1A1HPGDRAB9A | |
| SCHEMBL22729733 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1PDE10ABRPF1RAB9A | |
| SCHEMBL29839333 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1PDE10ABRPF1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | KMT2A 410/4885USP2 2804/4885ALDH1A1 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.