Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729593 | 0.90 | PNLIP (0.49) | RAB9AMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL22729483 | 0.88 | RAB9A (0.48) | RAB9AMEN1KMT2AHPGDBCAT2 | |
| SCHEMBL22729438 | 0.85 | GPR55 (0.55) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL22729541 | 0.84 | USP2 (0.64) | RAB9AKMT2AALDH1A1NPC1USP2 | |
| SCHEMBL29839397 | 0.82 | ALDH1A1 (0.47) | RAB9AMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL22729752 | 0.82 | ALDH1A1 (0.47) | RAB9AMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL29839338 | 0.81 | KMT2A (0.46) | RAB9AMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL22729624 | 0.81 | CNR2 (0.43) | BRD4 | |
| SCHEMBL22729486 | 0.81 | BRD4 (0.65) | RAB9AMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL22729733 | 0.81 | KMT2A (0.50) | RAB9AMEN1KMT2AALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | RAB9A 239/4885MEN1 1745/4885KMT2A 405/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | RAB9A 239/4885MEN1 1710/4885KMT2A 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.