Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL29839677

Cc1cc(C)cc([I+]c2c(C)cc(C)cc2C)c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.36
FFAR4 Q5NUL3 3/20 0.33
RAPGEF4 Q8WZA2 3/20 0.33
EPAS1 Q99814 1/20 0.32
KCNH2 Q12809 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C19 P33261 2/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 2/20 0.30
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30
PTGS2 P35354 2/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL31322589 0.91 FFAR4 (0.35) GPR3FFAR4PTGS2PTGS1
Trifluoromethanesulfonic Acid SCHEMBL29443425 0.90 GPR3 (0.40) GPR3FFAR4RAPGEF4EPAS1KCNH2
Trifluoromethanesulfonic Acid SCHEMBL5707355 0.88 GPR3 (0.41) GPR3FFAR4EPAS1KCNH2TSHR
Trifluoromethanesulfonic Acid SCHEMBL29462458 0.87 RAPGEF4 (0.41) GPR3FFAR4RAPGEF4KCNH2CYP1A2
Trifluoromethanesulfonic Acid SCHEMBL29462456 0.86 GPR3 (0.41) GPR3FFAR4RAPGEF4KCNH2CYP1A2
Trifluoromethanesulfonic Acid SCHEMBL29966478 0.86 HSD17B2 (0.34) GPR3FFAR4CYP1A2CYP3A4CYP2C19
Trifluoromethanesulfonic Acid SCHEMBL31135514 0.86 GPR3 (0.43) GPR3FFAR4RAPGEF4KCNH2CYP1A2
Trifluoromethanesulfonic Acid SCHEMBL30677458 0.85 SLC22A12 (0.32) GPR3EPAS1PTGS2
Trifluoromethanesulfonic Acid SCHEMBL31576455 0.83 KMT2A (0.37) GPR3FFAR4RAPGEF4MEN1KMT2A
Trifluoromethanesulfonic Acid SCHEMBL29462457 0.83 MAPT (0.37) GPR3FFAR4CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111410603-B Benzanthrone derivative, preparation method thereof and application thereof in functional pigment 上海甘田光学材料有限公司 2022-12-16 CN disclosed
CN-111440137-B 3, 4-benzocoumarin derivative and preparation method and application thereof 华东理工大学 2022-08-16 CN disclosed